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The Court of Appeal affirmed a decision dismissing assertions by Accord Healthcare, Sandoz and Teva that chemists would have deemed it 'immediately obvious' to create Astellas' patented cancer therapy, enzalutamide, because the expert evidence failed to explain why a particular atomic group would have been selected by chemists. The Xtandi patent is held by the University of California and is licensed on an exclusive basis to Astellas Pharma Inc. Writing for a panel of three justices in November 2024, Judge Richard Arnold said the judge was entitled to treat that omission as relevant when evaluating the expert’s evidence. The generics contended that a poster and presentation slides had disclosed a molecule akin to Astellas' claimed enzalutamide. According to the Court of Appeal judgment, they argued that the irresistible conclusion was that the patented invention was obvious. The claimed compound is differentiated by a defined substituent on its lower ring—an atom or set of atoms replacing a hydrogen on the hydrocarbon ring...
What is nuclear energy? Nuclear energy is the power released from the core of an atom (the ‘nucleus’). It can be produced in two ways: Fission — the split of a large atom into smaller atoms; Fusion — the joining of lighter atoms to create heavier atoms. Nuclear (fission) power plants split uranium atoms inside a reactor through fission. The heat generated produces steam, which turns a turbine to generate electricity. While fission is currently used commercially to produce energy, nuclear fusion is not yet commercially viable. See: What is the future of nuclear power generation in the UK? below. Various countries around the world are increasingly turning to nuclear energy to satisfy the rising need for clean energy and to strengthen their energy security. What is the nuclear fuel cycle? The set of industrial processes that results in electricity from nuclear reactions is known as the nuclear fuel cycle. It starts with the mining of uranium (or other ores...